Sassafras Southern Bistro
The Whaley Group
If you’re thinking about moving to Greenville, South Carolina, you’re in for more than just pretty views and friendly neighbors. This town is packed with amazing food—and Sassafras Southern Bistro is one place you can’t miss. Located right on Main Street in the heart of downtown, this cozy and upscale Southern spot is perfect for date nights, family dinners, or a relaxing evening with friends.
From mouthwatering shrimp and grits to the kind of desserts that make you wish for extra room, Sassafras feels like a delicious slice of the South. And once you walk in and see the charming brick walls and local art, you’ll know right away—it’s more than just a restaurant. It’s part of what makes Greenville feel like home.
A Little History with a Lot of Heart
Sassafras Southern Bistro has been serving Greenville for years, becoming a local favorite for both longtime residents and first-time visitors. Their goal? To blend classic Southern flavors with a touch of something special. The warm staff, beautiful atmosphere, and thoughtful menu keep people coming back again and again.
Inside, you’ll find exposed brick, cozy lighting, and art created by local artists—all coming together to make you feel right at home.
What’s on the Menu? Southern Comfort at Its Best
Get ready to eat well. Sassafras offers a wide range of dishes with something for everyone. Here are a few favorites you don’t want to miss:
⭐ Appetizers to Start
Blue Crab & Pepperjack Nachos – A house specialty packed with flavor and perfect for sharing.
Fried Green Tomatoes with Pimento Cheese – Crispy, cheesy, and topped with just the right drizzle of honey mustard.
Spicy Pork Tenderloin Bites – Tossed in buffalo sauce and served over creamy grits. Comfort food heaven.
🍤 Signature Dishes
Charleston Shrimp & Grits – Spicy tasso ham, fresh shrimp, and a white wine chicken sauce over creamy grits.
Filet Mignon with Pimento Cheese – A juicy steak topped with house-made pimento cheese and served with mashed potatoes.
Seafood Tr`io – Scallops, shrimp, and catfish grilled or blackened and served with creamy risotto and sautéed asparagus.
🥗 Light and Fresh
Try a dinner salad topped with grilled chicken, shrimp, salmon, or even steak medallions.
The Wedge Salad and Spinach Salad are popular picks for those wanting something crisp and refreshing.
🍰 Don’t Forget Dessert
Although the dessert menu changes, guests often rave about the rich cakes and seasonal treats—so be sure to save room!
The Vibe: Upscale, Cozy, and Full of Southern Charm
From the moment you walk in, Sassafras wraps you in warm lighting, historic brickwork, and soft music. It’s upscale without being stuffy—perfect for special celebrations or a relaxing night out. Outdoor seating is available when the weather’s nice, and the bar is fully stocked with local beer, cocktails, and a strong wine selection.
It’s a place where everyone—from out-of-towners to Greenville regulars—feels welcome.
Recognized and Loved by Many
While Sassafras Southern Bistro may not be covered in awards, it shines where it matters most: in the hearts of its guests. With glowing reviews online and years of loyal customers, it’s clearly a Greenville treasure. The combination of Southern classics, a thoughtful setting, and top-tier service makes it a standout in downtown’s busy dining scene.
Plan Your Visit
📍 Location: 103 N Main St #107, Greenville, SC 29601
📞 Phone: +1 864-235-5670
🌐 Website: sassafrasbistro.com
🕔 Hours: Open daily for dinner from 5:00 PM
💺 Reservations: Available via OpenTable
🍹 Service Highlights:
- Happy hour food
- Great cocktails
- Free Wi-Fi
- Outdoor seating available
Why Sassafras is a Must-Visit in Greenville
Whether you’re moving to Greenville or just passing through, Sassafras Southern Bistro is the kind of place that captures what this town is all about—warmth, flavor, and community. It’s a cozy corner filled with Southern hospitality, amazing food, and an atmosphere that feels like a warm hug.
Stop by, take a seat, and taste what makes Greenville feel like home.